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Saint-Petersburg, Russia

194156

Location

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Hereditary diseases of cats

Hereditary diseases of cats

CSD014
Mucopolysaccharidosis type VI
MPSVI
10
Cats
Some breeds
  • English mastiff
  • English pointer
  • English Setter (Llewellyn)
  • English springer spaniel
  • English toy terrier
  • Appenzeller mountain dog
  • Macaw
  • Harlequin miniature

Hereditary diseases
Mucopolysaccharidosis type VI is characterized by the accumulation of glycosaminoglycans (mucopolysaccharides) in many cells of the body, in particular cells of the liver, skin, muscles, bone marrow, and leukocytes. In sick animals, growth retardation, skeletal deformation (flattened muzzle with wide-set eyes and small ears), enlarged liver, and corneal opacity occur. The first symptoms usually appear at the age of 6-8 weeks, when skeletal deformity leads to the development of a "creeping" gait, and progress up to 9 months, after which the condition can stabilize.
Autosomal recessive inheritance
ARSB
N
M
000666-9685
8910299