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Hereditary diseases of cats

CSD006
Glycogenosis type IV of Norwegian forest cats
GSD IV
5
Cats
Some breeds
American akita
Hereditary diseases
Glycogenosis (Glycogen Storage Disease, GSD) is a group of autosomal recessive diseases resulting from impaired glycogen metabolism. The main and most versatile energy source for humans, animals and plants is glucose. In animals, glucose is stored in the form of glycogen, which is deposited in the form of granules in the cytoplasm of cells, mainly in the cells of the liver and muscles. With a lack of glucose, glycogen is broken down and glucose enters the bloodstream. The conversion of glycogen to glucose is a multistep process that occurs under the influence of a number of enzymes, the disruption of which leads to an excessive accumulation of glycogen in the form of abnormal granules and disruption of glucose homeostasis. Sick kittens die of hypoglycemia shortly after birth. In some cases, the animal lives up to six months, while suffering from progressive muscle degeneration.
Autosomal recessive inheritance
GBE1
N
M