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Dog hereditary diseases

DSD051
Congenital keratoconjunctivitis sicca and ichthyosiform dermatosis
CKCSID
10
Dogs
Hereditary diseases

Description
The disease has an autosomal recessive inheritance pattern. The first signs appear from birth as a weakened hydration of the cornea of ​​the eye due to reduced tearing of the lacrimal glands, accompanied by itching along the spine to the sides. In some cases, there is hyperpigmentation of the skin in the abdomen. Later, the disease affects the hair structure of the coat, leading to curly hair, which can spread both throughout the body and in certain areas, in some cases can lead to alopecia (baldness), in severe cases, there are secondary disorders of the structure of the teeth, changes in bite , seborrhea, gum problems, abnormalities in the structure of the nails and keratinization (hyperkeratinization) of the pads, leading to constant itching.

The disease is progressive, dogs are constantly anxious, with age the burden of clinical disorders leads to death.

Diagnostics
Characteristic changes in the behavior and physiology of the dog.

  • Autosomal recessive inheritance

    AR
    MM - sick
    NM - healthy, carrier
    NN is healthy
FAM83H
Cavalier king charles spaniel
Individual breeds