Dog hereditary diseases

DSD115
Sensory Neuropathy Border Collie
SN
5
21
Dogs
Sensory Neuropathy Border Collie Type
Hereditary diseases
Autosomal recessive inheritance
FAM134B
N
M
Border Collie
Individual breeds
Severe neurological disease caused by degeneration of sensory and, to a lesser extent, efferent (motor) nerve cells. The first clinical signs appear between 2 and 7 months of age. Progressive proprioceptive ataxia with intermittent tingling of the paws, hyperextension of the extremities, and self-induced wounds in the distal extremities. The first and most pronounced, usually, the pelvic limbs are affected. Also, in some cases, autonomic disorders such as urinary incontinence and regurgitation are noted. Proprioception and nociception in all limbs is reduced, leading to muscle atrophy, non-healing wounds with foci of necrosis. The prognosis is poor.