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Dog hereditary diseases

DSD128
Early progressive Greyhound polyneuropathy (GHPN)
10
Dogs
Hereditary diseases

"Description will be added"

Neurodegenerative pathology characterized by demyelination of nerve tissue cells with axonal dystrophy. The first clinical signs appear between the ages of 3 and 9 months. There is an intolerance to physical exertion, difficulties arise when walking - the puppy raises its paws high, in some cases, movements similar to the jumping of a rabbit are noted in the early stages of the disease. In the later stages, the disease is characterized by severe muscular atrophy, ataxia, and dysphonia. There were no behavioral impairments such as mental retardation or learning difficulties. With age, ataxia progresses, tetraparesis is noted, there is a pronounced delay in proprioceptive reactions, hyporeflexia, atrophy of the distal limbs and inductive stridor, gait disturbance appears - a short step, myotatic reflexes are reduced or absent. In some cases, paresis of the intercostal muscles and diaphragm may occur, which will lead to respiratory failure.
Greyhound
Individual breeds
Hereditary neurodegenerative pathology, there is intolerance to physical exertion, spasmodic movement, up to severe muscle atrophy, ataxia.