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Dog hereditary diseases

DSD117
Cardiomyopathy and juvenile mortality
CJM
10
Dogs
Hereditary diseases
Autosomal recessive inheritance
YARS2
N
M
  • Belgian shepherd
  • Belgian shepherd Malinois
  • Belgian shepherd Tervuren

Individual breeds
Lethal systemic pathology. Puppies die after birth or before 8 weeks of age. It is clinically manifested either by sudden death, or by the rapid development of a wide variety of symptoms - respiratory failure, anemic mucous membranes, myopathy, neurological disorders of varying severity, disruption of the gastrointestinal tract — vomiting, diarrhea. Laboratory blood tests reveal lactic acidosis, hyperazotemia and hyperlipidemia, sideroblastic anemia (iron deficiency in erythrocytes, a significant decrease in the color index). Pathological changes are characteristic of cardiomyopathy.