ATTENTION!

For the duration of the hostilities, the work of the Representative Office in Ukraine is temporarily suspended!
ZOOGEN is out of politics, we sincerely sympathize with everyone unwittingly drawn into the conflict and wish it a speedy end! Peace to all!

If you cannot contact the Representative Office in Ukraine - call our phones, write to e-mail and social networks! We will definitely answer and help you!

Under any circumstances, the ZOOGEN Company confirms its obligations to carry out studies, as well as for the prepaid coupons sold, regardless of the political situation.

Dog hereditary diseases

DSD101
Leonberger hereditary polyneuropathy type 1
LPN1
10
Dogs
Laryngeal Paralysis, ARHGEF10-related
Hereditary diseases
Autosomal recessive inheritance
ARHGEF10
N
M
  • Leonberger
  • St. Bernard

Individual breeds
The main signs of polyneuropathy are paralysis of the larynx and weakness of the hind limbs, accompanied by impaired coordination, developing at different times. There is a specific hoarse cough, especially after eating or drinking, the barking tone changes. In sick animals, increased fatigue and shortness of breath are observed. In the latter stages of the disease, stridor develops - a high-pitched sound made when breathing, which is an indicator of a serious problem. The disease can develop before the age of 1 year and up to 11 years.