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Dog hereditary diseases

DSD102
Leonberger hereditary polyneuropathy type 2
LPN2
10
Dogs
Hereditary diseases
Autosomal dominant inheritance with incomplete penetrance
GJA9
N
M
Leonberger
Individual breeds
The mutation leads to denervation of the motor muscles, in connection with which weakness, hypotension, and muscle atrophy develop. Other symptoms include laryngeal paralysis, change in barking tone, respiratory stridor, and shortness of breath. The disease can develop before the age of 1 year and up to 11 years. The disease is often diagnosed at a later stage.