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Dog hereditary diseases

DSD103
Neuronal ceroid lipofuscinosis type 5
NCL5
10
Dogs
Hereditary diseases
Autosomal recessive inheritance
CLN5
N
M
  • Australian cattle dog
  • Border Collie

Individual breeds
A disease associated with the accumulation of autofluorescent cytoplasmic antibodies in the cells of the nervous system. Affected dogs usually have a state of cerebellar dysfunction in which voluntary muscle movement tends to lead to loss of control and coordination. Symptoms (age 18-24 months): loss of vision, impaired coordination, changes in behavior (aggression, hyperactivity and dementia).