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Description
Progressive Retinal Atrophy (PRA) is the general name for a group of retinal diseases that damage photoreceptor cells (rods and cones) until their death.
A mutation in the RPGRIP1 gene (retinitis pigmentosa GTPase regulator-interacting protein 1 gene) leads to progressive retinal atrophy cord1 (PRA cord1). This type of progressive retinal atrophy is characterized by cone-rod dystrophies (hence the name of the disease - cord1). The first signs of the disease, which can be recorded ophthalmologically, appear at the age of about six months. DNA test detects PRA cord1 from the first days of life.
Diagnostics
Characteristic changes in the behavior and physiology of the dog.
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