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Dog hereditary diseases

DSD070
Achromatopsia
ACHM
10
Dogs
Hereditary diseases

Achromatopsia (ACHM, often referred to as cone degeneration, cd) is a congenital disorder in which the cells in the retina (cones) responsible for color vision are malformed. These cells are essential for daytime vision, which is why the disease is also called "day blindness".

Symptoms
The first symptoms in affected dogs begin to appear between 8-12 weeks of age. The disease is characterized by decreased visual acuity, fear of light, nystagmus and complete color blindness. In low light conditions, when other photoreceptor cells, called rods, are more responsible for vision, the visual quality of affected dogs does not deteriorate and is comparable to that of healthy dogs.

Diagnostics
Characteristic changes in the behavior and physiology of the dog.

  • Autosomal recessive inheritance

    AR
    MM - high risk of developing the disease, will transmit the disease allele to the offspring

    NM - there is no risk of developing a disease associated with this mutation, carrier - can transmit the disease allele to offspring

    NN - there is no risk of developing a disease associated with this mutation, cannot transmit the disease allele to offspring
CNGB3, CNGA3
N - norm
M - mutation
  • German shepherd
  • German shepherd longhaired
  • German shorthaired pointer
  • Labrador retriever

Individual breeds