Dog hereditary diseases

DSD073
Cerebellar abiotrophy
NCCD
10
25
Dogs
Neonatal cerebellar cortical degeneration
Hereditary diseases

Description
Cerebellar abiotrophy of beagle is a neurodegenerative disease associated with impaired functioning of the cerebellum, and, as a result, motor skills. As the disease progresses, neuronal degeneration in the cerebellar cortex progresses.

Symptoms
Symptoms include: loss of coordination and balance, standing with legs apart, tremors. The main histopathological lesions of the cerebellum characterizing the disease are destruction of Purkinje cells and secondary lesions in the granular layer. The first signs appear at about 3 weeks of age and progress slowly.

Diagnostics
Characteristic changes in the behavior and physiology of the dog.

  • Autosomal recessive inheritance

    AR
    MM - sick
    NM - healthy, carrier
    NN is healthy
SPTBN2
Beagle
Individual breeds